Void Volume Treatment

 

Location:

Detection tab page
Report Variable (Detection Parameters)

Type:

Switch

Dimension:

---

Value Range

On; Off

Default:

Off

Related Parameters:

Inhibit Integration

Description:

Use this parameter to hide a negative peak at the chromatogram start. This is especially useful for the negative water peak in ion chromatography. If Void Volume Treatment is set to On, peak detection is disabled for the range of the negative water peak.

Function:

The system searches for the negative water peak in the retention time range between Void Volume Treatment = On and Void Volume Treatment = Off. The negative water peak is the peak with the lowest signal at the retention time. Peak suppression is enabled for the time between Void Volume Treatment = On and the end of the negative water peak. The chromatogram is recorded, but it is not integrated. (This corresponds to Inhibit Integration = On.) Peak detection is enabled again only after the peak end of the negative water peak has been detected. (This corresponds to Inhibit Integration = Off.)

 Tip:

The Void Volume Treatment parameter becomes active only when its time is set before the start of the negative water peak.

 Note:

 

For each chromatogram, there can only be one range in which the negative water peak is detected. If you have defined several Void Volume Treatment = On and Void Volume Treatment = Off commands, the negative water peak is searched in the first defined range.

 

If you have selected a range in the chromatogram using the right mouse button and if you have set Void Volume Treatment to On via the Set Void Volume Treatment command on the context menu, this overwrites all previously defined ranges.

If Void Volume Treatment is not set to Off, Chromeleon uses the end of the chromatogram as the end of the range.

 

For information about how to use individual detection parameters, refer to Working with Chromatograms  Defining Detection Parameters Graphically.