Performance Qualification (PQ)

Instrument and software validation is becoming increasingly important to analytical laboratories. Performance Qualification (PQ) is an important aspect of validation. PQ is defined as "the process of demonstrating that an instrument consistently performs according to a specification appropriate for its routine use" [P. Bedson and M. Sargent, Accred. Qual. Assur. (1996) 1, 265-274.]

The task of PQ is both to ensure and to document that your system functions as required by your particular (routine) operation. The frequency and scope of Performance Qualification are determined by the requirements in your laboratory. They can be specified in internal instructions or in an SOP. The parameters should be similar to those for routine operation. In addition to Performance Qualification, Operational Qualification and Installation Qualification are important factors for validating instruments and software. The term AutoQ includes the three qualification procedures.

To perform Performance Qualification for your instruments, select Instrument PQ on the Qualification menu in the Chromeleon Browser. For more information, refer to Validation, AutoQ, and System Wellness  Instruments Operational and Performance Qualification.