Finding the Fastest ChromatogramSimulating Chromatograms
Finding the Fastest Chromatogram
Virtual Column provides an option that lets you optimize a separation for speed rather than for peak resolution.
To select this option, right-click on the Resolution Response Surface and select Find Fastest Chromatogram on the menu, or select the option on the Criterion menu on the Chromeleon menu bar. Enter the minimum acceptable resolution and click OK.
Virtual Column finds the eluent condition that gives the fastest chromatogram that satisfies the currently selected resolution criterion.
The example below shows the results of a Find Fastest Chromatogram command. The minimum acceptable resolution entered was 1.5. Notice that the eluent concentration selection bar was moved from 24.912 to 29.459 mM and the chromatogram time was reduced from 11.8 to 10.5 minutes.
